Product Details:
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Purity: | 99.0%min | Type: | Pharmaceutical Intermediates |
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Cas No.: | 1401708-83-5 | Product Name: | Dihexa |
Color: | White Powder | Storage: | Cool And Dry Place |
Shelf Life: | 2 Years | Application: | Organic Intermediate |
Moq: | 1kg | Whatsapp: | +8615512123605 |
Packing: | Aluminium Foil Bag | Package: | Aluminum Foil Bag |
High Light: | Dihexa Peptide APIs,Dihexa Powder CAS 1401708-83-5 |
Product Name: |
wj1@gzwjsw.com whatsapp +8615512123605 signal +66980528100 |
Product Name: | Dihexa |
Synonyms: | Dihexa;Hexanoyl-Tyr-Ile-Ahx-NH2;N-hexanoic-Try-Ile-(6)-amino hexanoic amide;PNB-0408;Dihexa (PNB-0408);N-(1-OXOHEXYL)-L-TYROSYL-N-(6-AMINO-6-OXOHEXYL)-L-ISOLEUCINAMIDE;L-Isoleucinamide, N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)- |
CAS: | 1401708-83- 5 |
MF: | C27H44N4O5 |
MW: | 504.66 |
EINECS: | 227-005-2 |
Product Categories: | |
Mol File: | 1401708-83- 5 |
Description
Peptide Supplements Oligopeptide Drug PNB-0408 Dihexa CAS 1401708-83-5
Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factory
Dihexa CAS 1401708-83-5 Specifications
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Product Name | Dihexa |
Synonyms | Dihexa |
CAS | 1401708-83-5 |
MF | C27H44N4O5 |
MW | 504.66 |
EINECS | 227-005-2 |
Mol File | 1401708-83-5.mol |
Boiling point | 866.2±65.0 °C |
Density | 1.111±0.06 g/cm3 |
Pka | 9.83 |
Dihexa CAS 1401708-83-5 Uses
Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (Kd=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease.
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