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Product Details:
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Purity: | 99%min | Application: | Pharmaceutical Intermediates |
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Type: | Pharmaceutical Intermediates | Appearance: | Transparent Liquid |
Cas No.: | 79-03-8 | Product Name: | Propionyl Chloride |
Packing: | Customers' Requirement | Cas: | 79-03-8 |
Shelf Life: | 2 Years | Whatsapp: | 008615512123605 |
Product Name: |
propionyl chloride |
Synonyms: | PROPIONYL CHLORIDE FOR SYNTHESIS;AKOS BBS-00004085;Propionyl chloride, 98.5%;PROPIONIC ACID CHLORIDE;Propionyl chloride Propanoyl chloride;PROPIONYL CHLORIDE;PROPANOYL CHLORIDE;Propionyl Chloride Factory Price |
CAS: | 79-03-8 |
MF: | C3H5ClO |
MW: | 92.52 |
EINECS: | 201-170-0 |
Mol File: | 79-03-8 |
Melting point | -94 °C |
Boiling point | 77-79 °C (lit.) |
density | 1.059 g/mL at 25 °C (lit.) |
vapor density | 3.2 (vs air) |
vapor pressure | 106 hPa (20 °C) |
refractive index | n20/D 1.404(lit.) |
Fp | 53 °F |
storage temp. | Store below +30°C. |
form | Liquid |
color | Clear |
PH Range | <7.0 |
explosive limit | 3.6-11.9%(V) |
Water Solubility | REACTS |
FreezingPoint | -94℃ |
Sensitive | Moisture Sensitive |
Merck | 14,7828 |
BRN | 385632 |
InChIKey | RZWZRACFZGVKFM-UHFFFAOYSA-N |
CAS DataBase Reference | 79-03-8 |
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Chemical Properties | Propionyl chloride is a colorless to light yellow liquid with a pungent odor. soluble in ethanol, decomposition in water. It is an easily flammable reagent and is corrosive. It is used for the introduction of the propionyl group and for the synthesis of propionate esters because of its high reactivity. |
Uses | Propionyl chloride is an chemical intermediate in the preparation of various propionic acid derivatives, It can also be used: To convert anisole to 4-methoxypropiophenone and 2-methoxynaphthalene to 1-propio-2-methoxynaphthalene in the presence of Indium(III) chloride (InCl3) impregnated mesoporous Si-MCM-41 catalyst. For chlorination in the presence of sulfuryl chloride and peroxides to form α-chloropropionyl chloride and β-chloropropionyl chloride. In reaction with (hydroxypropyl)cellulose to form the propanoate ester, [(propionyloxy)propyl]cellulose. |
Uses | Propionyl chloride is used as an intermediate in the production of agrochemicals and pharmaceuticals. It serves as an intermediate for dyes, textile auxiliaries and peroxide compounds. It acts as a crop protecting agent. |
Preparation | Propionyl chloride is synthesized by reacting propionic acid with phosphorus trichloride at 40-50°C for 1h, cooling, standing, separating and distilling to obtain the product. CH3CH2COOH+PCl3→CH3CH2COCl+HOPCl2 Propionyl chloride is industrially produced by chlorination of propionic acid with phosgene: CH3CH2CO2H + COCl2 → CH3CH2COCl + HCl + CO2 |
General Description | A colorless liquid with a pungent odor. Flash point of 50°F. Corrosive and very irritating to skin and eyes. Used to make other chemicals |
Packing | 1kg/bag ,25kg/bag;25kg/drum; according to your requirements | |||
Transit | Fedex, TNT,DHL,EMS,and so on. | |||
Port | Shanghai/Tianjin/Dalian/Beijing/Xi'an | |||
Lead Time | 1-3 working days upon received the payment | |||
For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea. |
Air & Water Reactions | Highly flammable. Propionyl chloride reacts vigorously or violently with water to form propionic acid and hydrochloric acid [Merck 11th ed. 1989]. |
Reactivity Profile | Acid halides, such as Propionyl chloride, are water reactive; some are violently reactive. They are incompatible with strong oxidizing agents, alcohols, amines, and alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. |
Hazard | Strong irritant to skin. |
Health Hazard | May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. |
Fire Hazard | Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. |
Safety Profile | A corrosive irritant to skin, eyes, and mucous membranes. Dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. Reacts with water or steam to produce toxic and corrosive fumes. Exothermic reaction with diisopropyl ether produces much gas. The reaction may be dangerous if confmed. To fight fire, use CO2, dry chemical; do not use water. When heated to decomposition it emits lughly toxic fumes of Cl-. See also HYDROCHLORIC ACID. |
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