|
Product Details:
|
| Type: | Anesthetic Agents | Cas No.: | 721-50-6 |
|---|---|---|---|
| Other Names: | Prilocaine | Purity: | 99% |
| Usage: | Used As A Local Anesthetic | Application: | Fine Chemical Intermediate |
| Appearance: | White Powder | Shelf Life: | 2 Years |
| Packing: | Aluminum Foil Bag /drum | Whatsapp: | +8615512123605 |
Product Detail
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form, it is often used in dentistry. It is also often combined with as a topical preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia.
| Product name | Prilocaine |
| CAS No. | 721-50-6 |
| MF | C13H20N2O |
| MW | 220.31 |
| EINECS No. | 211-957-0 |
| Melting point | 37-38° |
| Boiling point | bp0.1 159-162° |
| Density | 1.0117 (rough estimate) |
| Storage | 2-8°C |
| Solubility | Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent). |
Use: Labeled Indications
Local anesthesia: Production of local anesthesia in dentistry by nerve block or infiltration techniques.
Contraindications
Hypersensitivity to local anesthetics of the amide type or any component of the formulation; patients with congenital or idiopathic methemoglobinemia
Canadian labeling: Additional contraindications (not in US labeling): Citanest Plain Dental: Severe shock or heart block; inflammation or sepsis in the region of proposed injection
Adverse Reactions
Degree of adverse effects in the central nervous system and cardiovascular system are directly related to the blood levels of local anesthetic. The effects below are more likely to occur after systemic administration rather than infiltration.
Frequency not defined.
Cardiovascular: Bradycardia, cardiac arrest, cardiovascular signs and symptoms (stimulation/depression), circulatory shock, edema, hypotension
Central nervous system: Apprehension, confusion, convulsions, dizziness, drowsiness, euphoria, localized warm feeling, loss of consciousness, nervousness, numbness, oral paresthesia (may be persistent), sensation of cold, twitching
Dermatologic: Dermal ulcer, urticaria
Gastrointestinal: Vomiting
Hematologic & oncologic: Methemoglobinemia
Hypersensitivity: Anaphylactoid reaction, hypersensitivity reaction
Neuromuscular & skeletal: Tremor
Ophthalmic: Blurred vision, diplopia
Otic: Tinnitus
Respiratory: Respiratory arrest, respiratory depression
Dosage
Missed Dose
Since this medicine is usually given prior to a surgical procedure, the likelihood of missing a dose is very low.
Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected
25kg/drum,Cartons,Foil bags or as customer requirements . The goods of small quantity will be sent out in 3 working days. For bulk cargo, we will book the cargo space once the order is confirmed. Usually we will arrange the shipment in 7-15 days
Contact Person: admin
Tel: 18120567669
