Local anesthesia: Production of local anesthesia in dentistry by nerve block or infiltration techniques.

Contraindications

Hypersensitivity to local anesthetics of the amide type or any component of the formulation; patients with congenital or idiopathic methemoglobinemia

Canadian labeling: Additional contraindications (not in US labeling): Citanest Plain Dental: Severe shock or heart block; inflammation or sepsis in the region of proposed injection

Adverse Reactions

Degree of adverse effects in the central nervous system and cardiovascular system are directly related to the blood levels of local anesthetic. The effects below are more likely to occur after systemic administration rather than infiltration.

Frequency not defined.

Cardiovascular: Bradycardia, cardiac arrest, cardiovascular signs and symptoms (stimulation/depression), circulatory shock, edema, hypotension

Central nervous system: Apprehension, confusion, convulsions, dizziness, drowsiness, euphoria, localized warm feeling, loss of consciousness, nervousness, numbness, oral paresthesia (may be persistent), sensation of cold, twitching

Dermatologic: Dermal ulcer, urticaria

Gastrointestinal: Vomiting

Hematologic & oncologic: Methemoglobinemia

Hypersensitivity: Anaphylactoid reaction, hypersensitivity reaction

Neuromuscular & skeletal: Tremor

Ophthalmic: Blurred vision, diplopia

Otic: Tinnitus

Respiratory: Respiratory arrest, respiratory depression

Dosage
Missed Dose
Since this medicine is usually given prior to a surgical procedure, the likelihood of missing a dose is very low.
Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected