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Product Details:
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| Purity: | 99%min | Application: | Pharmaceutical Intermediates |
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| Type: | Syntheses Material Intermediates | Appearance: | White Powder |
| Cas No.: | 171599-83-0 | Product Name: | Sildenafil Citrate |
| Packing: | Fiber Carton | Shelf Life: | 2 Years |
| Moq: | 1kg | Whatsapp: | +8615512123605 |
| High Light: | carton packing Male Sexual Enhancement 171596-29-5,Vardenafil Sex Drug |
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Quick detail
Product name: Varde nafil hydrochloride
Other name: Levitra
CAS: 224785-91-5
Grade: Pharmaceutical grade
Package: Disguised package ; Foil bag
Delivery date: 3-5 work days
Customized: Customized
Suitable for: Elderly, Adult
Purity: >99%
Appearance: White Crystalline Powder
Market: Global
White Crystalline Powder
Trademark: Pharmlab
Certification: GMP, ISO 9001, USP
Usage:Erectile Dysfunction Treatment, Male Sex Enhancer
Payment: T/T, Western Union and Money Gram
Certification: GMP, HSE, ISO 9001, USP, BP
Delivery: Within 24hours After Your Payment
Varde nafil is a centrally-acting phosphodiesterase 5 inhibitor that is clinically used to treat erectile dysfunction. Vard enafil also exhibits antioxidative and antihypertensive activities and shows some potential for synergistic chemotherapeutic ability through its modulation of cGMP-NO signaling. This compound increases expression of NO and eNOS as well as activity of superoxide dismutase, decreasing oxidative stress, pulmonary vascular resistance, and right ventricular hypertrophy and increasing cardiac output in animal models of pulmonary arterial hypertension. Varde nafil decreases proteinuria and glomerular damage in animal models of diabetic nephropathy-induced cGMP pathway dysfunction. In cellular models, varde nafil decreases secretion of IL-8 and expression of oxidative LDLR, suggesting potential benefit in the treatment of benign prostatic hyperplasia/low urinary tract syndrome.
Varden afil Applications:
Vard enafil is a PDE5 inhibitor used for treating erectile dysfunction. Varden afil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to citrate and Tadal afil. The difference between the Varde nafil molecule and citrate is that a nitrogen atom has different position and the change of piperazine ring methyl group to an ethyl group. Tad alafil is structurally different from both and Vard enafil. Varde nafil's relatively short effective time is comparable to but somewhat lon ger than .
Vard enafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vard enafil might provoke potentially life-threatening hypotension .
Vard enafil Specification:
| Test Items | Specification | Test Results |
| Description | White or almost white crystalline powder | White crystalline powder |
| Melting Point | 191.0~193.0ºC | 192ºC |
| Loss of drying | ≤1.0% | 0.5% |
| Heavy Metal | ≤20ppm | 15ppm |
| TLC | Only one spot | Only one spot |
| Assay | ≥99.5% | 99.91% |
| Conclusion | It complies with the USP 32. | |
Chemical Name |
Silden afil citrate |
|---|---|
Synonyms |
Via gra,Sild enafilcitrate;1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazinecitratesalt;5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[5,4-e]pyrimidin-7-onecitratesalt;1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine,2-hydroxy-1,2,3-propanetricarboxylate;Silden afilCitrate(100mg);Silde nafilcitrate,>=99%;Silden afilcitrate,Professionalsupply;5-[2-Ethoxy-5-[(4-methyl-piperazin-1-yl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-onecitrate |
CAS No. |
171599-83-0 |
Molecular Formula |
C28H38N6O11S |
Molecular Weight |
666.7 |
Melting point |
187-189°C |
Storage condition |
2-8°C |
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| Packing | 1kg/bag ,25kg/bag;25kg/drum; according to your requirements | |||
| Transit | Fedex, TNT,DHL,EMS,and so on. | |||
| Port | Shanghai/Tianjin/Dalian/Beijing/Xi'an | |||
| Lead Time | 1-3 working days upon received the payment | |||
| For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea. |
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