Local Anesthetic Drugs Propitocaine Hydrochloride / Propitocaine HCL CAS 1786-81-8

Propitocaine hydrochloride

Product Name: Propitocaine hydrochloride
Synonyms: 2-(propylamino)-o-propionotoluidide hydrochloride;2-(propylamino)-o-propionotoluididmonohydrochloride;alpha-propylamine-2-methyl-propionanilidehydrochloride;citanesthydrochloride;l-67hydrochloride;n-(2-methylphenyl)-2-(propylamino)-propanamidmonohydrochloride;prilocainechloride;xylonest
CAS: 1786-81-8
MF: C13H21ClN2O
MW: 256.77
EINECS: 217-244-0
Chemical Properties White Solid
Usage antibacterial
Usage Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with  as a preparation for dermal anesthesia (pril ocaine or EMLA), for treatment of conditions like paresthesia.
Usage Anesthetic (local).

Propitocaine hydrochloride Introduction:

1. Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with as a preparation for dermal anesthesia (EMLA), for treatment of conditions like paresthesia.

2. Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid.

3. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), , Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include  (Xylocaine),

4. Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest).