Basic Description:

Product name: Propitocaine hydrochloride

Synonyms: 2-(Propylamino)-o-propionotoluidide hydrochloride; alpha-propylamino-2'-methylpropionanilide hydrochloride; Citanest; N-(2-Methylphenyl)-2-(propylamino)-propanamide hydrochloride; N-(a-propylaminopropionyl)-o-toluidine hydrochloride; Prilocaine hydrochloride; Xylonest; ; N-(2-methylphenyl)-N~2~-propylalaninamide hydrochloride (1:1); Propitocaine HCL; Prilocaine HCl

CAS No.: 1786-81-8

EINEC No.: 217-244-0

Assay: 99%

Packing: 25kg/drum

M.F.: C13H21ClN2O

M.W.: 256.7716

InChI: InChI=1/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,

1-3H3,(H,15,16);1H

Molecular Structure:

Boiling point: 361.6 C at 760 mmHg

Flash point: 134.3 C

Steam pressure: 2.05E-05mmHg at 25 C

Appearance: White crystalline powder

Description:
Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes

Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined

with lidocai ne as a preparation for dermal anesthesia (lidoc aine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia. In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.

Application:
Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine

is also often combined with lidoca ine as a preparation for dermal anesthesia (lid ocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.

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