Raw Hydrochloride 98% CAS 119356-77-3 USP For PE

Hydrochloride

Synonyms: d- hydrochloride; DL- hydrochloride
CAS: 129938-20-1
Assay: 98% min.
Packing: 1kg net/foil bag or tin.
Delivery: Express courier.
MF: C9H7ClN2O5
MW: 258.62

Character: White to Off-White Cyrstalline Solid, odorless, slight sweet taste, Mp 175-177°C, optical rotation +128°
Usage: Selective serotonin reuptake inhibitor (SSRI), pharmaceutical material, hormone.


Product Description:

Applications:
Hydrochloride:Randomized, double blind, placebo-controlled trials have confirmed the efficacy of for the treatment of PE. Different dosage has different impacts on different type of PE. 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of 30 mg in men with lifelong PE, but there is no difference in men with acquired PE. , given 1-3 hours before episode, prolongs IELT, increases the sense of control and satisfaction in men of 18 to 64 years of age with PE. Since PE is associated with personal distress, interrelationship difficulty, provides help for men with PE to overcome this condition. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as . and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing libido and causing erectile dysfunction. , on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.

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Phenacetin	62-44-2
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