Sorry! This product is no longer available.

Product Details:
|
Purity: | 99%min | Application: | Pharmaceutical Intermediates |
---|---|---|---|
Type: | Syntheses Material Intermediates | Appearance: | White Powder |
Cas No.: | 171596-29-5 | Product Name: | Tad Alafil |
Packing: | Fiber Carton | Shelf Life: | 2 Years |
Moq: | 1kg | Whatsapp: | +8615512123605 |
Wickr: | Wanjiang |
Description
Product Name: |
Tadal afil whatsapp +8615512123605
signal +66980528100
|
Synonyms: | TADALA FIL;;IC 351;(6R,12AR)-6-(benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido;GF 196960;ICOS 351;Tildenafil;UK 336017 |
CAS: | 171596-29-5 |
MF: | C22H19N3O4 |
MW: | 389.4 |
EINECS: | 687-782-2 |
Mol File: |
Melting point | 298-300°C |
alpha | D20 +71.0° |
Boiling point | 679.1±55.0 °C(Predicted) |
density | 1.51±0.1 g/cm3(Predicted) |
Fp | 2℃ |
storage temp. | Sealed in dry,2-8°C |
solubility | DMSO: soluble20mg/mL, clear |
pka | 16.68±0.40(Predicted) |
form | powder |
color | white to beige |
optical activity | [α]/D +68 to +78°, c = 1 in chloroform-d |
InChIKey | WOXKDUGGOYFFRN-IIBYNOLFSA-N |
CAS DataBase Reference | 171596-29-5 |
Description:
Tad alafil (Tadalifil citrate), a phosphodiesterase type 5 inhibitor, is used to treat erectile dysfunction (ED) and decreased libido in males. Tad alafil works by aiding relaxation of blood vessels and increasing blood flow in the during sexu al arousal, resulting in improved erectile function. Tad alafil is much longer lasting. Effects can be felt anywhere between 36-48 hours.
Action: Tada lafil improves erectile function significantly, possibly increased sex al activity, and is very safe.
There are limited side effects associated with its use. The most common side effects are headache, upset stomach, back pain, and muscle aches, and usually subside with in a few hours.
Tada lafil was also found to be significantly higher at the end of the month, due to increased sex ual activity.
Applications:
Tad alafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Tadal afil, and under the name Adcirca for the treatment of pulmonary arterial hypertension.
Tadala fil's pharmacologic distinction is its longer half-life (17.50 hours) resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadala fil's daily therapeutic use in relieving pulmonary arterial hypertension.
Specifications:
Test Items | Specification | Test Results |
Appearance | White powder | Conforms |
Test method | High pressure liquid chromatography(HPLC) | Conforms |
Melting Point | 300℃~303℃ | 301.5℃-302.6℃ |
Loss on drying | ≤0.5% | 0.24% |
Heavy metals(Pb) | ≤20ppm | 7.5ppm |
Residue on ignition | ≤0.1% | 0.08% |
Relative substance | ≤1.0% | 0.145% |
Assay (on dried basis) | ≥98.5% | 99.33% |
Conclusion | The product conform to USP 32. |
Product name: Varden afil hydrochloride
CAS: 224785-91-5
Grade: Pharmaceutical grade
Package: Disguised package ; Foil bag
Delivery date: 3-5 work days
Customized: Customized
Suitable for: Elderly, Adult
Purity: >99%
Appearance: White Crystalline Powder
Market: Global
White Crystalline Powder
Trademark: Pharmlab
Certification: GMP, ISO 9001, USP
Usage:Erectile Dysfunction Treatment, Male Sex Enhancer
Payment: T/T, Western Union and Money Gram
Certification: GMP, HSE, ISO 9001, USP, BP
Delivery: Within 24hours After Your Payment
Varde nafil is a centrally-acting phosphodiesterase 5 inhibitor that is clinically used to treat erectile dysfunction. Varde nafil also exhibits antioxidative and antihypertensive activities and shows some potential for synergistic chemotherapeutic ability through its modulation of cGMP-NO signaling. This compound increases expression of NO and eNOS as well as activity of superoxide dismutase, decreasing oxidative stress, pulmonary vascular resistance, and right ventricular hypertrophy and increasing cardiac output in animal models of pulmonary arterial hypertension. Var denafil decreases proteinuria and glomerular damage in animal models of diabetic nephropathy-induced cGMP pathway dysfunction. In cellular models, varden afil decreases secretion of IL-8 and expression of oxidative LDLR, suggesting potential benefit in the treatment of benign prostatic hyperplasia/low urinary tract syndrome.
Varde nafil Applications:
Varde nafil is a PDE5 inhibitor used for treating erectile dysfunction. Var denafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to citrate and Tad alafil. The difference between the Varde nafil molecule and citrate is that a nitrogen atom has different position and the change of piperazine ring methyl group to an ethyl group. Tada lafil is structurally different from both and Varden afil. Varde nafil's relatively short effective time is comparable to but somewhat lon ger than .
Vard enafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Varde nafil might provoke potentially life-threatening hypotension .
Varden afil Specification:
Test Items | Specification | Test Results |
Description | White or almost white crystalline powder | White crystalline powder |
Melting Point | 191.0~193.0ºC | 192ºC |
Loss of drying | ≤1.0% | 0.5% |
Heavy Metal | ≤20ppm | 15ppm |
TLC | Only one spot | Only one spot |
Assay | ≥99.5% | 99.91% |
Conclusion | It complies with the USP 32. |
Phenacetin | 62-44-2 |
Benzocaine | 94-09-7 |
Benzocaine hydrochloride | 23239-88-5 |
Boric acid | 11113-50-1 |
Pregabalin | 148553-50-8 |
Levamisole (hydrochloride) | 16595-80-5 |
Levamisole phosphate | 32093-35-9 |
Tetracaine | 94-24-6 |
Tetracaine hydrochloride | 136-47-0 |
Procaine (hydrochloride) | 51-05-8 |
Procaine | 59-46-1 |
Tetramisole hydrochloride | 5086-74-8 |
Tetramisole | 14769-73-4 |
Xylazine | 7361-61-7 |
Xylazine HCl | 23076-35-9 |
larocaine hcl | 553-63-9 |
Larocaine/Dimethocaine | 94-15-5 |
2-Phenylethylamine Hydrochloride | 156-28-5 |
Panadol | 103-90-2 |
sodium borohydride | 16940-66-2 |
Contact Person: Michelle fiona
Tel: +8615512123605