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Product Details:
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| Purity: | 99%min | Application: | Pharmaceutical Intermediates |
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| Type: | Syntheses Material Intermediates | Appearance: | White Powder |
| Cas No.: | 330784-47-9 | Product Name: | Avanafil |
| Packing: | Fiber Carton | Shelf Life: | 2 Years |
| Moq: | 1kg | Whatsapp: | +8615512123605 |
| Wickr: | Wanjiang | Signal: | 0066980528100 |
| High Light: | CAS 330784-47-9 Avanafil Powder,ED Treatment Male Sex Enhancement |
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ED Treatment Male Sex Enhancement CAS 330784-47-9 Avanafil Powder
Quick detail
| Product name : | Avanafil |
| Assay : | 99% min. |
| CAS: | 330784-47-9 |
| Molecular Formula: | C23H26ClN7O3 |
| Molecular Weight: | 483.95 |
| Melting point: | 150-152°C |
| Density: | 1.372 |
| MF: | |
| Storage condition: | Refrigerator |
| Character: | White to Off-White Cyrstalline Solid. |
Usage: | Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. |
| Categories: | Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API's. |
High Purity Male Sex Hormones Avanafil CAS 330784-47-9 For Sex Strength
Product Name: Avanafil
Synonyms: (S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine;4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;Avanafil;Avanafil (usan/inn);D03217;4-[[(3-Chloro-4-)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide;4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide;(S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide
CAS: 330784-47-9
MF: C23H26ClN7O3
MW: 483.95
Chemical Properties White Solid
Usage Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM.
Usage A phosphodiesterase
Avanafil Applications:
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum, as well as the retina. Other similar drugs . The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30–45 minutes. About two-thirds of the participants were able to engage in activity within 15 minutes.
Avanafil Functions:
an oral selective pde5 inhibitor indicated for the treatment of erection dysfunction. The average of effective time is 16 minutes. The plasma concentration can reach peak after two hours, the half-life is 18~48hours. Even is five days, the purity of can be tested in blood. The clinical report shows that it can be up to 83% after taking, and the dosage is 25-35mg. The main advantages are little side-effect, lasting for a long time and working strongly in two or three days.
Avanafil COA
| Test Items | Specification | Results |
| Appearance | White or almost white powder | Complies |
| Identification | IR,HPLC | Complies |
| Loss on drying | ≤0.5% | 0.23% |
| Heavy metals | ≤10ppm | <10ppm |
| Residue on Ignition | ≤0.1% | 0.05% |
| Single impurity | ≤0.5% | 0.19% |
| Purity(on dried basis) | ≥99.0% | 99.4% |
| Conclusion | Product complies with In-house Standard. | |
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