99% Procaine Hydrochloride CAS 51-05-8 Local Anesthesia Drugs

 Product Name: Procaine hydrochloride
Synonyms: aminocaine;anadolor;anesthesol;anestil;;Benzoicacid,monohydrochloride;benzoicacid,monohydrochloride;bernocaine
CAS: 51-05-8
MF: C13H21ClN2O2
MW: 272.77
EINECS: 200-077-2
Assay: 99%
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Description & Application:
The primary use for procaine is as a topical anaesthetic.
Procaine is used less frequently today since more effective (and hypoallergenic) alternatives such as  (Xylocaine) exist. It has been discontinued from US markets.
 
Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is a vasodilator, and is often coadministered with epinephrine for the purpose of vasoconstriction. Vasoconstriction helps to reduce bleeding, increases the duration and quality of anesthesia, prevents the drug from reaching systemic circulation in large amounts, and overall reduces the amount of anesthetic required, a vasoconstrictor, procaine does not have the euphoric and addictive qualities that put it at risk for abuse.   manufactures also use procaine as an additive at ratios ranging from 1:1 up to 10%  with 90% procaine, which can be life-threatening.
 
Procaine, an ester anesthetic, is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-amino benzoic acid (PABA), which is then excreted by the kidneys into the urine.
 
A 1% procaine injection has been recommended for the treatment of extravasation complications associated with venipuncture (along with moist heat, ASA, antibiotics). It has likewise been recommended for treatment of inadvertent intra-arterial injections (10 ml of 1% procaine), as it helps relieve pain and vascular spasm.
 
Procaine is an occasional additive in illicit street drugs