Prilocaine Descriptions:
Prilocaine is a local anesthetic that is similar pharmacologically . Prilocaine binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. Action potential propagation and never function is, therefore, prevented. This block is reversible and when the drug diffuses away from the cell, sodium channel function is restored and nerve propagation returns. Prilocaine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers. Currently, Prilocaine is used most often for infiltration anesthesia in dentistry.

Prilocaine is local anesthetic used to numb a person's skin and tissues. This medication is often made available as a cream that is topically applied, but it may also be available in an injectable form, which should always be administered by a specially trained professional. Its effects are not instant, but once a person experiences the associated numbness it may last for hours.

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form (trade name Citanest), it is often used in dentistry.