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Product Details:
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| Purity: | 99.0%min | Type: | Pharmaceutical Intermediates |
|---|---|---|---|
| Cas No.: | 23964-57-0 | Product Name: | Articaine Hydrochloride |
| Color: | Light Yellow Powder | Storage: | Cool And Dry Place |
| Shelf Life: | 2 Years | Moq: | 10g |
| Whatsapp: | +8615512123605 | Delivery Time: | In 3 Days Send Out |
| Payment Term: | T/t Bank Transfer / Btc | Payment Way: | WU |
| High Light: | Articaine HCl Powder 23964-57-0,CAS 23964-57-0 |
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| Product Name | Articaine Hydrochloride |
| Synonyms | methyl 4-methyl-3-[[(1-oxo-2-(propylamino)propyl]amino]-2-thenoate monohydrochloride; Carticaine HCl; Ultracaine; CARTICAINE HYDROCHLORIDE; Ultracain;Articaine hydrochloride; Methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate hydrochloride; 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylic acid methyl ester hydrochloride |
| CAS | 23964-57-0 |
| MF | C13H20N2O3S.ClH |
| MW | 320.839 |
| Purity | 98% min |
| EINECS | 245-957-7 |
| Appearance | White Powder |
| Categories | Local anesthetic; Pharmaceutical intermediate |
Product name: Articaine Hydrochloride ;Articaine HCl
CAS:23964-57-0
MF:C13H20N2O3S.HCl
MW:320.839
EINECS:245-957-7
Product Categories:local anesthetic;Pharmaceutical intermediate
Appearance: White crystalline powder
Trademark: Pharmlab
Original: China
Grade: Pharmaceutical grade
Certificate: ISO 9001, USP,GMP
Payment: Western Union, MoneyGram, T/T, bitcoin
Shipping: EMS,HKEMS,EUB,ETK,FEDEX,DHL,UPS,Aramex,ETC
Description
Articaine is an intermediate-potency, short-acting amide local anesthetic with a fast metabolism due to an ester group in its structure. It is effective with local infiltration or peripheral nerve block in dentistry, when administered as a spinal, epidural, ocular, or regional nerve block, or when injected intravenously for regional anesthesia.
In comparative trials, its clinical effects were not generally significantly different from those of other short-acting local anesthetics like prilocaine, and chloroprocaine, and there is no conclusive evidence demonstrating above-average neurotoxicity. Articaine proved to be suitable and safe for procedures requiring a short duration of action in which a fast onset of anesthesia is desired, eg, dental procedures and ambulatory spinal anesthesia, in normal and in special populations.
Structure and metabolism
The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed
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