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Product Details:
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Purity: | 99% | Type: | Pharmaceutical |
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Cas No.: | 7361-61-7 | Usage: | Animal Pharmaceuticals |
Product Name: | Xylazine | Appearance: | White Powder |
Shelf Life: | 2 Years | Sample: | Available |
Application: | Pharmaceutical Raw Intermediates | Color: | White Fine Powder |
Test Method: | HPLC | Whatsapp: | +8615512129801 |
Moq: | 1kg | Signal: | +66988010565 |
Wickr: | Wanjiangchem888 | Email: | Wj2@gzwjsw.com |
Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor.Veterinarians also use xylazine as an emetic, especially in cats.
Xylazine is often used as a sedative, muscle relaxant, and analgesic. It is frequently used in the treatment of tetanus.
Xylazine, acting as an agonist at alpha-2 adrenergic receptors, decreases the release of norepinephrine and dopamine in the central nervous system resulting in effects such as analgesia, sedation and muscle relaxation.
Basic info
Chemical Name |
Xylazine |
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Synonyms |
2-(2,6-dimethylanilino)-5,6-dihydro-4h-1,3-thiazine; 2-(2,6-dimethylphenylamino)-4h-5,6-dihydro-1,3-thiazine; 5,6-dihydro-2-(2,6-xylidino)-4h-1,3-thiazine; 5,6-dihydro-2-(2,6-xylidino)-4h-3-thiazine; 2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine; XylazineBase&HCL; Xylazine,2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazinehydrochloride; Xylazine |
CAS No. |
7361-61-7 |
Molecular Formula |
C12H16N2S |
Molecular Weight |
220.33 |
Melting point |
140 C |
Boiling point |
334.2±52.0 °C(Predicted) |
CAS 7361-61-7 Xylazine 99% Purity white powder Pharma Raw Material
Porduct Description:
Product Name: | Xylazine |
CAS No: | 7361-61-7 |
Molecular formula: | C12H16N2S |
EINECS No.: | 230-902-1 |
Melting point: | 140°C |
Boiling point: | 334.2±52.0 °C(Predicted) |
Place of Origin: | China |
Type: | Pharmaceutical intermediates |
Appearance: | Powder |
Color: | White |
Purity: | 99.9% |
Packing: | 25kg/cartoon box |
pka: | 7.67±0.20(Predicted) |
Storage: | -20°C |
Sample: | Available |
Description:
*Xylazine is an agonist of α2-adrenergic receptors (Ki = 194 nM). It is an analog of clonidine, an α2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard (Item No. 22641).
Functions and Applications:
*Antinociceptive;Alpha-2 adrenergic agonist
*Xylazine is an α2 class of adrenergic receptor agonist. Xylazine is a clonidine analoque that acts on presynaptic and postsynaptic receptors as an a 2-adrenergic agonist.
Description | Xylazine is an agonist of α2-adrenergic receptors (Ki = 194 nM). It is an analog of clonidine, an α2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard (Item No. 22641). |
Originator | Xylazine,Bayer |
Uses | Antinociceptive;Alpha-2 adrenergic agonist |
Uses | Xylazine is an α2 class of adrenergic receptor agonist. Xylazine is a clonidine analoque that acts on presynaptic and postsynaptic receptors as an a 2-adrenergic agonist. |
Manufacturing Process | 2,6-Dimethylphenyl isothiocyanate, 31.0 g (0.2 mole), prepared from 2,6- dimethylaniline with thiophosgene, were added dropwise during 15 min to a well-stirred suspension of 15.0 g (0.2 mole) of 3-aminopropanol-1 in 100 ml of ether. The ether started to boil. Stirring under reflux was continued for 30 min, and the ether was then distilled off. The residue was treated with 100 ml of concentrated hydrochloric acid and boiled under reflux for 30 min. After cooling, it was diluted with water, filtered free from impurities, and the base was precipitated by the addition of concentrated sodium hydroxide solution. When recrystallized from benzene-ligroin, the resulting compound 2-(2,6- dimethyl-phenylamino)-4H-5,6-dihydro-1,3-thiazine, melting point 140-142°C (yield 90% of the theoretical). |
Therapeutic Function | Analgesic, Anesthetic |
General Description | Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions. |
Biochem/physiol Actions | Xylazine when used along with keta mine is considered to be a potent and safe anaesthetic in experimental animal. It is known to elevate the hepatic release of glucose, which aggravates to hyperglycemia. |
Safety Profile | Poison by ingestion, subcutaneous, and intravenous routes. Human systemic effects: change in motor activity, fall in blood pressure, miosis, pleural thickening, pulse rate decrease, somnolence. When heated to decomposition it emits very toxic fumes of NOx and SOx |
Melting point | 140 C |
Boiling point | 334.2±52.0 °C(Predicted) |
density | 1.0905 (rough estimate) |
refractive index | 1.5700 (estimate) |
storage temp. | -20°C |
solubility | Soluble in methanol at 50mg/ml. Also soluble in dilute acid solutions. |
pka | 7.67±0.20(Predicted) |
CAS DataBase Reference | 7361-61-7(CAS DataBase Reference) |
Hazard Codes | T,Xi |
Risk Statements | 25-36/37/38 |
Safety Statements | 45-37/39-26 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | XJ0776300 |
HazardClass | 6.1 |
HS Code | 2934990002 |
Toxicity | LD50 in mice (mg/kg): 43 i.v.; 121 s.c.; 240 orally; LD50 in rats (mg/kg): 130 orally (Sagner) |
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