Blood System Agents Pregabalin Pharmaceutical raw materials Lyrica 148553-50-8

COA:

Application:
LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a
clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a
polyethylene-lined closure. The oral solution contains 20 mg/mL of pregabalin, along with
methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.

Pregabalin is indicated for:

1.Treatment of neuropathic pain from diabetic neuropathy or post herpetic neuralgia. There is not enough data to state that it should be used in all neuropathic pain.
2.Adjunctive therapy in adults with partial seizures with or without secondary generalization
3.Fibromyalgia
4.Generalized anxiety disorder
5.Alcohol Withdrawal
Usually physicians will start the patient on a low dose of pregabalin and increase it gradually, depending on the patient's evaluation. Its therapeutic effect appears after 1 week of use and is similar in effectiveness , and venlafaxine but pregabalin has demonstrated superiority by producing more consistent therapeutic effects for psychic and somatic anxiety symptoms. Long-term trials have shown continued effectiveness without the development of tolerance and additionally unlike benzodiazepines it does not disrupt sleep architecture and produces less severe cognitive and psychomotor impairment; it also has a low potential for abuse and dependence and may be preferred over the benzodiazepines for these reasons

 

 

 

Function:
1. Pharmacological efficacy: Pregabalin CAS 148553-50-8 is a novel γ -aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release
2. The main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
3. Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Can also be used to treat pain and anxiety.