Podophyllotoxin (abbreviated as PPT), otherwise known as podofilox, is a non-alkaloid toxin lignan extracted from the roots
andrhizomes of Podophyllum species.Under the trade names Condylox, a gel, and Wartec, a solution or cream, it is used on the skin as a topical treatment of external genital warts, caused by some types of the human papillomavirus (HPV), and other warts. PPT and its synthetic derivatives display a wide selection in medical applications such as purgative, vesicant, antirheumatic, antiviral,
and antitumor agents. These derivatives include etoposide, teniposide, and etopophos. Their anticancer activity has been
heavily under study and used in various chemotherapies, including lung cancer, lymphomas, and genital tumors.
Function
1. Podophyllotoxin is mainly used in treat acuity condyloma.
2. Podophyllotoxin has the effect in relieving rheumatism, prevent cough and ache, invigorate the circulation of blood and detoxification.
3. As Antiviral agents.Podophyllotoxin can solve hot, diminish inflammation,ease pain, broken blood, efficiency promoting tissue regeneration.
4. Podophyllotoxin displays a range of activities such as cathartic, purgative, antiviral, vesicant, and antihelminthic.
5. Podophyllotoxin is also used as a gel or solution to treat genitalwarts with noticeably shorter duration and fewer side effects.